EU-LIFE

Building and promoting Excellence in Life Sciences in Europe
Building and promoting Excellence in Life Sciences in Europe

Events

There are no upcoming events.

Past Events

24 Nov 27 Nov 2015
Oeiras Portugal

Course description

The sequence of a genome alone does not carry enough information to fully understand how genomic processes are carried out in the cell nucleus; to achieve this, the knowledge of the three-dimensional (3D) architecture of a genome is necessary. Advances in genomic technologies and the development of new analytical methods, such as 3C-based methods, have allowed getting insights at unprecedented resolution into how the genome is organized. Recently, it has been shown that chromatin is organized in Topologically Associating Domains (TADs), large interaction domains that appear to be conserved among different cell types. In this course, participants will learn to use TADbit, a software for the analysis and modeling of Hi-C data.

The course will cover all the aspect of modeling with Hi-C data:
Generation of Hi-C contact matrices from raw data (that is, Hi-C specific quality check of the reads, mapping, filtering and normalization)
Analysis of Hi-C matrices (Hi-C map visualization, TAD identification, experiment comparison, and TAD selection)
3D modeling and analysis of TADs
The 3D module of TADbit is based on a computational module of the Integrative Modeling Platform (IMP, http://www.integrativemodeling.org) that uses chromosome conformation capture data to determine the 3D architecture of genomic domains and entire genomes at unprecedented resolutions.
Participants can bring-in specific biological questions and/or their on data to work on during the course.
At the end of the course, participants will be familiar with the TADbit software, enabling them to fully analyze and model Hi-C data.
Target Audience

The course is oriented to experimental researchers and bioinformaticians at the graduate and post-graduate levels. The last edition of this course was attended by people with different backgrounds and interested in the genome organization.
Moreover, Hi-C data have recently been used in metagenomics studies to accurately cluster metagenome assembly contigs into groups that contain nearly complete genomes of each species.
It is likely that the participants to this course aim at getting involved in generating Hi-C data for chromosome structure determination or that they just want to be able to correctly interpret and analyze publicly available data.

http://gtpb.igc.gulbenkian.pt/bicourses/CSDM15

IMPORTANT DATES for this Course:
Deadline for applications: November 15th 2015
Notification of acceptance within 72 hours of application (working days count)
Course date: November 24th to November 27th 2015

CSDM15 Course duration: 4 days CSDM15 Course Fee: Euro 360.00

6 Oct 2015
Helsinki Finland

The Building Bridges symposia series is arranged to bridge clinical and basic/translational research and provide examples of how teams of investigators are working together to advance personalized

2 Sep 4 Sep 2015
Brno Czech Republic

This conference will be our first conference with speakers from both CEITEC and ICRC to explore the interface of the life sciences and mater

19 Jul 1 Aug 2015
Oeiras Portugal

In the Summer School “Host-microbe symbioses – old friends and foes” we will explore stable host-microbe interactions as a spectrum from parasitic to mutualistic. It is becoming clear that most animals and plants associate with microbes during their life and that these greatly influence host biology. The course will last two weeks and will explore this field with leading scientists that bring a broad range of expertise and approaches.
The Summer School will be targeted at second or later years PhD students (from Europe).

12 May 13 May 2015
Copenhagen Denmark

This 2nd EU-LIFE scientific workshop will bring together basic scientists and clinicians/translational researchers to explore and discuss epigenetics in relation to disease.

11 May 12 May 2015
Copenhagen Denmark

The 3rd EU-LIFE Strategy Meeting will take place at the BRIC in Copenhagen, Denmark.

9 Feb 10 Feb 2015
Brussel Belgium

Join VIB at its first conference on ‘Structural dynamics in cellular communication’ that will take place in an architecturally significant venue in the heart of Europe (Brussels, Belgium) from 9-1