Building and promoting Excellence in Life Sciences in Europe
Building and promoting Excellence in Life Sciences in Europe

Bioinformatician (Full-time or Part-time)


We wish to recruit a highly motivated Bioinformatician to participate in a project investigating epigenetic patterning in oocytes and how chromatin programmes gene expression states in the embryo. The project follows recent insights into the role of transcription in patterning epigenetic states in the oocyte, and the elucidation of mechanisms underlying atypical histone modification patterns in oocytes.
The project as a whole will focus on how chromatin states are established during oogenesis and their impact on transcriptional regulation. It will investigate the extent of and mechanisms underlying the persistence of oocyte-derived chromatin states in the embryo, and how this leads to imprinting in different developmental lineages. These questions will be investigated through a combination of approaches, including innovative, single-cell multi-omic and genome-wide analysis. Much of the work will be in mouse models, but we expect to explore parallels in human oocytes and embryos.
The successful applicant will join an interactive, multidisciplinary team in the Epigenetics Programme in the laboratory of Dr Gavin Kelsey. For more information on the work of the Kelsey’s group, please visit
The ideal candidate must have a PhD in Bioinformatics, computational biology, molecular biology or related discipline with strong Bioinformatics component. The post holder must have excellent working knowledge of epigenomic and transcriptomic analyses and relevant experience in programming in some of the main languages used in Bioinformatics.
The position would be suitable for an experienced Bioinformatics Researcher or for a Molecular or Developmental Biologist with experience in Bioinformatics, who welcomes the challenge of integrating genome-scale datasets to gain insight into epigenetic processes.
Funding for this position is available for up to 3 years in the first instance.

Please indicate on your application your preference for full-time (37 hours per week) or part-time hours (minimum of 22 hours per week).
Starting salary is £30,751 per annum to £34,166 per annum (FTE) depending on experience.
Full details of the position can be found here.
On applying please quote reference BIF-GK-MRC
Closing date for completed applications is Monday 20 August 2018.
The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute’s ambitions and attracts highly motivated and talented people.
The Babraham Institute is a Disability Confident Employer and has a positive approach to employing disabled people.
The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.

As you will see, the person specification states the minimum knowledge, experience and skills required by the Institute to enable the person to do this job. When you are completing the application form you should remember that it will be used in assessing who should be shortlisted and invited for an interview. Please refer to the person specification and state your reasons for applying for the post, relating your knowledge, experience and skills gained either through work or voluntary activities, to the requirements of the job. If you wish to attach a c.v. or supplementary information please feel free to do so. To ensure no conflict of interest may arise, please indicate on your completed application whether or not you are related to any current member of Institute staff.

The Babraham Institute aims to promote equality of opportunity for all with the right mix of talent, skills and potential. The Babraham Institute welcomes applications from diverse candidates. Criminal records will be taken into account for recruitment purposes only when the conviction is relevant. Unless the nature of the work demands it, you will not be asked to disclose convictions which are 'spent' under the Rehabilitation of Offenders Act 1974. Having an 'unspent' conviction will not necessarily bar you from employment. This will depend on the circumstances and background to your offence(s).

However, all vacancies within our Nursery are exempt from the Rehabilitation of Offenders Act 1974 because the positions entail working with children.

The Babraham Institute is continually trying to find ways to reduce its administrative costs, as such we have made the decision not to write to those candidates who have not been shortlisted for interview. Therefore, please be aware that if you have not heard from us within one month of the closing date, you can assume that your application has been unsuccessful.

Host Institute