EU-LIFE

Building and promoting Excellence in Life Sciences in Europe
Building and promoting Excellence in Life Sciences in Europe

Postdoctoral Position in Computational Biology

Description

A postdoctoral position is immediately available in the group of Prof. Filippo Rijli at the Friedrich Miescher Institute for Biomedical Research (FMI). We apply a multidisciplinary experimental approach to investigate the role of transcription and epigenetic factors in chromatin regulation in vivo during mouse craniofacial and brain circuit development (selected references: Oury et al., Science 2006; Di Meglio et al., Science 2013; Bechara et al., Cell Reports 2015; Karmakar et al., Cell Reports 2017; Minoux et al. Science 2017). We are currently mapping chromatin states and generating 3D genome maps of identified neuronal subsets and cranial neural crest cell subpopulations. We aim at gaining a systems-level understanding of the regulatory principles of chromatin modifications in gene regulation by integrating available genetic, epigenetic, and expression data from high throughput sequencing technologies (including single cell and bulk RNAseq, ATACseq, ChIPseq, promoter capture Hi-Cseq, etc.). The successful candidate will join a computational PhD student already embedded in the Rijli group and co-supervised by the Head of the FMI Computational Group, Dr. Michael Stadler.

The candidate should have a PhD in Computational Biology, Physics, Computer Science or in an equivalent quantitative field, a track record in analyzing high throughput sequencing data and a strong interest in gene regulation and epigenetics. Experience with R/Bioconductor is a plus. Candidates are also expected to have first or co-first author publications in their respective field as well as written and oral communication skills. The position is funded for a minimal initial period of 2 years, with possibility of extension.

The FMI, affiliated with the University of Basel and the Novartis Institutes for Biomedical Research, is an international institute pursuing fundamental research (www.fmi.ch). It has a staff of 340 including about 200 postdoctoral fellows and graduate students. The FMI is situated in Basel, Switzerland, a city in the center of Europe offering an outstanding scientific and cultural environment.

Applications should be emailed to filippo.rijli@fmi.ch and include a motivation letter, CV and names and email addresses of at least two referees.

Prof. Filippo Rijli
http://www.fmi.ch/rijli.f
www.fmi.ch

Host Institute