Postdoctoral Research Scientist
We are seeking a Postdoctoral Research Scientist to join the Houseley laboratory. This position is funded through a Wellcome Trust award aimed at discovering the mechanisms by which useful, adaptive mutations such as copy number variation (CNV) form within complex genomes.
The successful candidate will use replicatively aged cohorts of budding yeast to quantify copy number variation (CNV) events in different environments, analysing individual cells by PFGE-southern blot. Particular attention will be given to the development of assays allowing measurement of de novo CNV frequency from single copy loci. Genetic methods will then be used to elucidate the mechanisms by which gene expression alters recombination rate.
The job will also involve a component of mammalian cell culture and analysis to aid ongoing work to translate our findings in yeast to humans. These studies lie at the interface of recombination, chromatin and gene expression, and will require a high level of proficiency in yeast handling and molecular biology.
The successful candidate must have a PhD in Molecular Biology and experience in design and implementation of novel statistical methods.
Funding for this position is available for up to one year.
Full details of the position can be found here.
Starting salary is £30,751 per annum
On applying please quote reference CNV-JH-LTC.
Closing date for completed applications is Monday 26th March 2018.
NO AGENCIES PLEASE
The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute’s ambitions and attracts highly motivated and talented people.
The Babraham Institute is a Disability Confident Employer and has a positive approach to employing disabled people.
The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.
As you will see, the person specification states the minimum knowledge, experience and skills required by the Institute to enable the person to do this job. When you are completing the application form you should remember that it will be used in assessing who should be shortlisted and invited for an interview. Please refer to the person specification and state your reasons for applying for the post, relating your knowledge, experience and skills gained either through work or voluntary activities, to the requirements of the job. If you wish to attach a c.v. or supplementary information please feel free to do so. To ensure no conflict of interest may arise, please indicate on your completed application whether or not you are related to any current member of Institute staff.
The Babraham Institute aims to promote equality of opportunity for all with the right mix of talent, skills and potential. The Babraham Institute welcomes applications from diverse candidates. Criminal records will be taken into account for recruitment purposes only when the conviction is relevant. Unless the nature of the work demands it, you will not be asked to disclose convictions which are 'spent' under the Rehabilitation of Offenders Act 1974. Having an 'unspent' conviction will not necessarily bar you from employment. This will depend on the circumstances and background to your offence(s).
However, all vacancies within our Nursery are exempt from the Rehabilitation of Offenders Act 1974 because the positions entail working with children.
The Babraham Institute is continually trying to find ways to reduce its administrative costs, as such we have made the decision not to write to those candidates who have not been shortlisted for interview. Therefore, please be aware that if you have not heard from us within one month of the closing date, you can assume that your application has been unsuccessful.